PRECISE will establish a cohort of 12,000 pregnant women across East, West and Southern Africa. With their consent we will collect biological samples and information about their lives, contexts and stories. This information will provide a unique and holistic data set that will be used to investigate the potential for introduction of novel methods to assist with diagnosis and management of placental disorders.

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While PRECISE is designed to answer specific research questions, a major legacy will be the highly-phenotyped representative cohorts of West, East and Southern African women and the creation of an incomparable African-based biorepository for future hypothesis-generated and -generating research. The core activity will be to collect environmental, social, geographical, demographic, clinical, and biological data related to three populations of women.